VRTX

Healthcare

Vertex Pharmaceuticals Incorporated · Biotechnology · $111B

UQS Score — Balanced Preset
71.6
Good

Vertex Pharmaceuticals Incorporated scores 71.6/100 using the Balanced preset.

81.4
Quality
35%
55.0
Moat
30%
63.7
Growth
20%
99.1
Risk
15%

VRTX — Key Takeaways

✅ Strengths

Vertex Pharmaceuticals Incorporated shows strong profitability and capital efficiency
Vertex Pharmaceuticals Incorporated shows solid revenue and earnings growth trajectory
Vertex Pharmaceuticals Incorporated shows conservative financial structure with manageable risk
Vertex Pharmaceuticals Incorporated shows attractive valuation relative to fundamentals

VRTX — Score History

65707580Apr 2Apr 3Apr 4Apr 5Apr 6Apr 7Apr 8
DateUQSQualityMoatGrowthRiskValueChange
Apr 8, 202671.681.455.063.799.165.90.0
Apr 7, 202671.681.455.063.799.165.90.0
Apr 6, 202671.681.455.063.799.165.90.0
Apr 5, 202671.681.455.063.799.165.9+0.2
Apr 4, 202671.481.455.063.799.164.90.0
Apr 3, 202671.481.455.063.799.164.90.0
Apr 2, 202671.481.455.063.799.164.9

VRTX — Pillar Breakdown

Quality

81.4/100 (25%)

Vertex Pharmaceuticals Incorporated demonstrates outstanding capital efficiency and profitability, placing it among the highest-quality businesses in the market.

Capital Efficiency (ROIC)Moderate

How effectively capital is deployed to generate returns.

Return on EquityStrong

Profitability relative to shareholders' equity.

Operating ProfitabilityStrong

Ability to convert revenue into operating profit.

Net ProfitabilityStrong

Bottom-line profit as a share of revenue.

Gross Profit / AssetsStrong

Asset productivity — how much gross profit each dollar of assets generates.

Cash GenerationWeak

Free cash flow relative to market value.

Growth

63.7/100 (20%)

Vertex Pharmaceuticals Incorporated demonstrates healthy growth trends across revenue and earnings.

Recent Revenue TrendWeak

Revenue trajectory over the last twelve months.

3Y Revenue CAGRWeak

Compound annual revenue growth rate over 3 years.

EPS GrowthStrong

Year-over-year earnings per share growth.

Forward Revenue OutlookModerate

Analyst consensus for future revenue growth.

Forward EPS GrowthStrong

Analyst consensus for future earnings growth.

Risk

99.1/100 (15%)

Vertex Pharmaceuticals Incorporated carries minimal financial risk with conservative leverage and strong solvency.

Financial LeverageStrong

Debt levels relative to earnings capacity.

Debt/EquityStrong

Total debt relative to shareholder equity.

Current RatioStrong

Short-term liquidity — ability to pay near-term obligations.

Interest CoverageStrong

Earnings capacity relative to interest payments.

Valuation

65.9/100 (15%)

Vertex Pharmaceuticals Incorporated trades at a reasonable valuation with decent earnings yield and FCF multiples.

Earnings YieldModerate

Inverse of forward P/E — higher yield means cheaper stock.

Price to Free Cash FlowModerate

How many years of FCF the market cap represents.

PEG RatioStrong

P/E relative to earnings growth — lower is more attractive.

Moat

55/100 (30%)

Vertex Pharmaceuticals Incorporated has meaningful competitive advantages that should protect its market position. The Moat pillar evaluates competitive advantages across five dimensions: Switching Costs, Network Effects, Cost Advantage, Intangible Assets, and Scale & Ecosystem. Sign in to customize moat ratings for VRTX.

Score Composition

Quality
81.4×25%20.4
Growth
63.7×20%12.7
Risk
99.1×15%14.9
Valuation
65.9×15%9.9
Moat
55.0×30%16.5
Total
71.6Good

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How is the VRTX UQS Score Calculated?

The UQS (Unified Quality Score) for Vertex Pharmaceuticals Incorporated is calculated using a proprietary 5-pillar framework with 25 financial metrics. Each pillar evaluates a different dimension on a 0–100 scale, then combines into a single weighted score. Scoring thresholds are calibrated per sector.

Quality (25%) measures profitability and capital efficiency — ROIC, ROE, margins, GP/Assets, and FCF Yield.

Moat (25%) assesses Vertex Pharmaceuticals Incorporated's competitive advantages across switching costs, network effects, cost advantages, intangible assets, and ecosystem scale.

Growth (20%) tracks revenue trajectory and earnings momentum, combining historical results with analyst forward estimates.

Risk (15%) is inversely scored — lower leverage and strong balance sheet health result in higher scores.

Valuation (15%) measures whether Vertex Pharmaceuticals Incorporated is fairly priced using earnings yield, price-to-FCF, PEG ratio, and EV/EBITDA relative to sector peers.

Six investor-inspired presets are available, each with different pillar weights: Balanced, Buffett, Munger, Lynch, Cathie Wood, and Graham. The public score shown here uses the Balanced preset. Learn more in our FAQ.