LYRA

Healthcare

Lyra Therapeutics, Inc. · Biotechnology

UQS Score — Balanced Preset
25.5
Weak

Lyra Therapeutics, Inc. scores 25.5/100 using the Balanced preset.

20.0
Quality
35%
10.0
Moat
30%
37.5
Growth
20%
70.2
Risk
15%

LYRA — Key Takeaways

✅ Strengths

Lyra Therapeutics, Inc. shows conservative financial structure with manageable risk

⚠️ Areas of Concern

Lyra Therapeutics, Inc. has below-average profitability metrics
Lyra Therapeutics, Inc. has limited competitive moat
Lyra Therapeutics, Inc. has stretched valuation metrics

LYRA — Score History

20253035Apr 2Apr 3Apr 4
DateUQSQualityMoatGrowthRiskValueChange
Apr 4, 202625.520.010.037.570.20.00.0
Apr 3, 202625.520.010.037.570.20.00.0
Apr 2, 202625.520.010.037.570.20.0

LYRA — Pillar Breakdown

Quality

20.0/100 (25%)

Lyra Therapeutics, Inc. currently shows below-average quality metrics, suggesting challenges with profitability.

Capital Efficiency (ROIC)Weak

How effectively capital is deployed to generate returns.

Return on EquityStrong

Profitability relative to shareholders' equity.

Operating ProfitabilityWeak

Ability to convert revenue into operating profit.

Net ProfitabilityWeak

Bottom-line profit as a share of revenue.

Cash GenerationWeak

Free cash flow relative to market value.

Growth

37.5/100 (20%)

Lyra Therapeutics, Inc. shows steady but unspectacular growth, typical for mature companies.

Recent Revenue TrendWeak

Revenue trajectory over the last twelve months.

3Y Revenue CAGRWeak

Compound annual revenue growth rate over 3 years.

EPS GrowthWeak

Year-over-year earnings per share growth.

Forward Revenue OutlookStrong

Analyst consensus for future revenue growth.

Risk

70.2/100 (15%)

Lyra Therapeutics, Inc. maintains a reasonable risk profile with manageable debt levels.

Financial LeverageStrong

Debt levels relative to earnings capacity.

Debt/EquityStrong

Total debt relative to shareholder equity.

Current RatioModerate

Short-term liquidity — ability to pay near-term obligations.

Interest CoverageWeak

Earnings capacity relative to interest payments.

Valuation

0.0/100 (15%)

Lyra Therapeutics, Inc. appears expensively valued relative to its fundamentals and growth prospects.

Moat

10/100 (30%)

Lyra Therapeutics, Inc. operates in a highly competitive environment with limited sustainable advantages. The Moat pillar evaluates competitive advantages across five dimensions: Switching Costs, Network Effects, Cost Advantage, Intangible Assets, and Scale & Ecosystem. Sign in to customize moat ratings for LYRA.

Score Composition

Quality
20.0×25%5.0
Growth
37.5×20%7.5
Risk
70.2×15%10.5
Valuation
0.0×15%0.0
Moat
10.0×30%3.0
Total
25.5Weak

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How is the LYRA UQS Score Calculated?

The UQS (Unified Quality Score) for Lyra Therapeutics, Inc. is calculated using a proprietary 5-pillar framework with 25 financial metrics. Each pillar evaluates a different dimension on a 0–100 scale, then combines into a single weighted score. Scoring thresholds are calibrated per sector.

Quality (25%) measures profitability and capital efficiency — ROIC, ROE, margins, GP/Assets, and FCF Yield.

Moat (25%) assesses Lyra Therapeutics, Inc.'s competitive advantages across switching costs, network effects, cost advantages, intangible assets, and ecosystem scale.

Growth (20%) tracks revenue trajectory and earnings momentum, combining historical results with analyst forward estimates.

Risk (15%) is inversely scored — lower leverage and strong balance sheet health result in higher scores.

Valuation (15%) measures whether Lyra Therapeutics, Inc. is fairly priced using earnings yield, price-to-FCF, PEG ratio, and EV/EBITDA relative to sector peers.

Six investor-inspired presets are available, each with different pillar weights: Balanced, Buffett, Munger, Lynch, Cathie Wood, and Graham. The public score shown here uses the Balanced preset. Learn more in our FAQ.