CLYM

Healthcare

Climb Bio, Inc. · Biotechnology · $750M

UQS Score — Balanced Preset
16.3
Poor

Climb Bio, Inc. scores 16.3/100 using the Balanced preset.

UQS vs Healthcare Sector
CLYM
16.3
Sector avg
32.4
Quality
Weak
Moat
Weak
Growth
Weak
Risk
Good
Valuation
Elevated

What is Climb Bio, Inc.?

Climb Bio, Inc. is a clinical-stage biotechnology company focused on developing treatments for autoimmune-driven inflammatory diseases. Headquartered in Wilmington, Delaware, the company is building a pipeline centered on a single lead therapeutic candidate.

Climb Bio is developing budoprutug, an anti-CD19 monoclonal antibody designed to target B cells involved in autoimmune disease. The company is pursuing indications including systemic lupus erythematosus, lupus nephritis, immune thrombocytopenia, and membranous nephropathy. As a clinical-stage company, Climb Bio does not yet generate product revenue — its business model depends on advancing its pipeline through clinical trials and securing future partnerships or approvals.

Climb Bio was incorporated in 2018 and rebranded from Eliem Therapeutics, Inc. in October 2024.

  • Budoprutug — anti-CD19 monoclonal antibody in clinical development
  • Systemic lupus erythematosus and lupus nephritis program
  • Immune thrombocytopenia therapeutic program
  • Membranous nephropathy therapeutic program

Is CLYM a Good Stock to Buy?

UQS Score rates CLYM as Poor overall, reflecting significant challenges across most of the five scoring pillars.

The one area where Climb Bio stands out relative to its overall profile is Risk, which earns a Good label — suggesting the company's balance sheet or near-term financial runway is relatively managed for a clinical-stage biotech. This is not uncommon for early-stage companies that have raised capital ahead of major expenditures.

Quality, Moat, and Growth all score Weak, reflecting the realities of a pre-revenue pipeline company with no established competitive advantages yet. Valuation is rated Elevated, meaning the current market price may not offer a margin of safety given the development-stage risks.

See the full pillar breakdown and underlying financial metrics by signing up for a UQS Pro account. Sign up free →

Past performance does not guarantee future results. UQS Score is based on fundamental data and is not a buy/sell recommendation.

Does CLYM pay dividends?

No — Climb Bio, Inc. does not currently pay a dividend.

Climb Bio does not pay a dividend, which is typical for clinical-stage biotechnology companies. All available capital is directed toward funding research, clinical trials, and pipeline advancement. Income-focused investors should not expect distributions from CLYM in the near term.

When does CLYM report earnings?

Climb Bio reports financial results on a quarterly cadence, consistent with US-listed public companies.

As a pre-revenue biotech, Climb Bio's quarterly reports focus primarily on cash position, operating expenses, and clinical development updates rather than traditional revenue or earnings metrics. Investors typically monitor pipeline milestones and trial readouts alongside financial disclosures.

For the most recent quarter's results and clinical updates, visit Climb Bio's investor relations page directly.

CLYM Price History

+84.1% over 5Y

Monthly close, adjusted for stock splits and dividend reinvestment.

Return Calculator

What if I invested in Climb Bio, Inc.?

$
Today it would be worth
$74,365
That's a +644% total return, or +644% annualized.

Based on Climb Bio, Inc.'s historical closing prices, adjusted for stock splits and dividend reinvestment. Past performance does not guarantee future results. This is for informational purposes only and is not financial advice.

CLYM Long-term Outlook

Climb Bio's fundamental outlook is shaped by the early stage of its pipeline. With Growth and Quality both rated Weak, the company faces the typical uncertainties of a clinical-stage biotech — trial outcomes, regulatory timelines, and capital needs are the primary variables. The Good Risk rating provides some reassurance around near-term financial stability, but the Elevated Valuation label suggests the market may already be pricing in optimistic scenarios.

Growth drivers

  • Clinical advancement of budoprutug across multiple autoimmune indications
  • Potential partnership or licensing deals as trial data matures
  • Growing unmet need in autoimmune disease treatment

Key risks

  • Clinical trial failure or delays in any key indication
  • Elevated valuation relative to development-stage fundamentals
  • Ongoing capital requirements typical of pre-revenue biotechs

CLYM vs Peers

Climb Bio operates in a competitive autoimmune and rare-disease biotech space alongside several other small-cap clinical and commercial-stage companies.

PROKCLYM scores lower
ProKidney Corp.

ProKidney focuses on cell therapy approaches for chronic kidney disease, representing a different modality than Climb Bio's antibody-based strategy.

ZVRACLYM scores lower
Zevra Therapeutics, Inc.

Zevra pursues rare and orphan disease indications with a broader pipeline, giving it a different risk and diversification profile.

RIGLCLYM scores lower
Rigel Pharmaceuticals, Inc.

Rigel has commercially approved products in hematology and autoimmune disease, placing it further along the development curve than Climb Bio.

Frequently Asked Questions

What does Climb Bio do?

Climb Bio is a clinical-stage biotechnology company developing therapies for autoimmune-driven inflammatory diseases. Its lead candidate, budoprutug, is an anti-CD19 monoclonal antibody being studied in conditions such as systemic lupus erythematosus, lupus nephritis, immune thrombocytopenia, and membranous nephropathy.

Does CLYM pay dividends?

No, Climb Bio does not pay a dividend. As a pre-revenue clinical-stage company, it reinvests all available capital into research and clinical development. Dividend income is not a realistic expectation for CLYM shareholders at this stage.

When does CLYM report earnings?

Climb Bio reports on a quarterly cadence, as required for US-listed public companies. Because it is pre-revenue, reports focus on cash runway and pipeline updates rather than traditional earnings. Check Climb Bio's investor relations page for the most current schedule.

Is CLYM a good stock to buy?

UQS Score rates CLYM as Poor overall. Quality, Moat, and Growth are all rated Weak, while Valuation is Elevated. The Risk pillar earns a Good label, which is a relative positive. Investors should weigh these factors carefully against their own risk tolerance before making any decision.

Is CLYM overvalued?

The UQS Valuation pillar for CLYM is rated Elevated, suggesting the current market price may not offer a comfortable margin of safety relative to the company's development-stage fundamentals. Pre-revenue biotechs often carry premium valuations based on pipeline potential rather than current financials.

How does CLYM compare to its competitors?

Compared to peers like Rigel Pharmaceuticals, which has approved commercial products, Climb Bio is at an earlier stage with a narrower pipeline. Rivals such as Zevra Therapeutics and ProKidney Corp. pursue different therapeutic modalities, making direct comparisons complex. The full UQS competitor breakdown is available to Pro members.

What is CLYM's market cap bracket?

Climb Bio is classified as a small-cap company. This places it in a segment of the market that typically carries higher volatility and liquidity risk compared to mid- or large-cap peers, which is common for clinical-stage biotechnology firms.

Who founded Climb Bio?

Climb Bio was incorporated in 2018 and operated under the name Eliem Therapeutics before rebranding in October 2024. Detailed founding information, including leadership history, is publicly available through the company's SEC filings and investor relations materials.

Is CLYM a long-term quality investment?

As a long-term quality indicator, the UQS Score rates CLYM as Poor. Weak scores across Quality, Moat, and Growth suggest the company has not yet established the durable fundamentals typically associated with long-term compounders. Clinical success could change this picture, but current metrics reflect significant uncertainty.

What is the main competitive advantage of Climb Bio?

Climb Bio's potential advantage lies in its focus on budoprutug's mechanism — targeting CD19-positive B cells across multiple autoimmune indications. However, the UQS Moat pillar is rated Weak, reflecting that no durable competitive advantage has been established at this stage of development.

What sector does CLYM belong to?

Climb Bio operates in the Healthcare sector, specifically within biotechnology. It focuses on the autoimmune and inflammatory disease sub-segment, which includes conditions with significant unmet medical need and active drug development competition.

Is CLYM a growth stock or value stock?

Based on UQS pillar labels, CLYM does not fit cleanly into either category. The Growth pillar is rated Weak and Valuation is Elevated, meaning the stock carries a premium price without demonstrated growth metrics to support it — a profile more speculative than either classic growth or value.

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Pro Analysis

CLYM — Score History

510152025Apr 2Apr 12Apr 22May 2May 12May 22May 24v5
Score changes· 4 most recent
DateUQSQualityMoatGrowthRiskValueChange
May 10, 202616.30.06.018.574.00.0+4.3
May 9, 202612.00.06.00.070.10.0-3.7
Apr 22, 202615.70.06.018.570.10.0-0.9
Apr 2, 202616.60.06.023.170.10.0

CLYM — Pillar Breakdown

Quality

0.0/100 (25%)

Climb Bio, Inc. currently shows below-average quality metrics, suggesting challenges with profitability.

Capital Efficiency (ROIC)Weak

How effectively capital is deployed to generate returns.

Return on EquityWeak

Profitability relative to shareholders' equity.

Operating ProfitabilityWeak

Ability to convert revenue into operating profit.

Net ProfitabilityWeak

Bottom-line profit as a share of revenue.

Cash GenerationWeak

Free cash flow relative to market value.

Growth

18.5/100 (20%)

Climb Bio, Inc. faces growth headwinds with declining or stagnant revenue trends.

Recent Revenue TrendWeak

Revenue trajectory over the last twelve months.

EPS GrowthStrong

Year-over-year earnings per share growth.

Forward Revenue OutlookWeak

Analyst consensus for future revenue growth.

Risk

74.0/100 (15%)

Climb Bio, Inc. maintains a reasonable risk profile with manageable debt levels.

Financial LeverageStrong

Debt levels relative to earnings capacity.

Debt/EquityStrong

Total debt relative to shareholder equity.

Current RatioStrong

Short-term liquidity — ability to pay near-term obligations.

Interest CoverageWeak

Earnings capacity relative to interest payments.

Valuation

0.0/100 (15%)

Climb Bio, Inc. appears expensively valued relative to its fundamentals and growth prospects.

Moat

6/100 (25%)

Climb Bio, Inc. operates in a highly competitive environment with limited sustainable advantages. The Moat pillar evaluates competitive advantages across five dimensions: Switching Costs, Network Effects, Cost Advantage, Intangible Assets, and Scale & Ecosystem. Sign in to customize moat ratings for CLYM.

Score Composition

Quality
0.0×25%0.0
Growth
18.5×20%3.7
Risk
74.0×15%11.1
Valuation
0.0×15%0.0
Moat
6.0×25%1.5
Total
16.3Poor

Financial Data

More Stock Analysis

How is the CLYM UQS Score Calculated?

The UQS (Unified Quality Score) for Climb Bio, Inc. is calculated using a proprietary 6-pillar framework with 29 financial metrics. Each pillar evaluates a different dimension on a 0–100 scale, then combines into a single weighted score. Scoring thresholds are calibrated per sector. Momentum is an optional Pro toggle — without it, you get the 5-pillar / 25-metric core shown below.

Quality (25%) measures profitability and capital efficiency — ROIC, ROE, margins, GP/Assets, and FCF Yield.

Moat (25%) assesses Climb Bio, Inc.'s competitive advantages across switching costs, network effects, cost advantages, intangible assets, and ecosystem scale.

Growth (20%) tracks revenue trajectory and earnings momentum, combining historical results with analyst forward estimates.

Risk (15%) is inversely scored — lower leverage and strong balance sheet health result in higher scores.

Valuation (15%) measures whether Climb Bio, Inc. is fairly priced using earnings yield, price-to-FCF, PEG ratio, and EV/EBITDA relative to sector peers.

Six investor-inspired presets are available, each with different pillar weights: Balanced, Buffett, Munger, Lynch, Cathie Wood, and Graham. The public score shown here uses the Balanced preset. Learn more in our FAQ.