ASND

Healthcare

Ascendis Pharma A/S · Biotechnology · $15B

UQS Score — Balanced Preset
53.4
Good

Ascendis Pharma A/S scores 53.4/100 using the Balanced preset.

UQS vs Healthcare Sector
ASND
53.4
Sector avg
32.4
Quality
Weak
Moat
Neutral
Growth
Strong
Risk
Neutral
Valuation
Neutral

What is Ascendis Pharma A/S?

Ascendis Pharma is a Denmark-based biopharmaceutical company focused on developing therapies for rare and underserved medical conditions. Its proprietary TransCon platform powers a pipeline spanning endocrinology and oncology.

Ascendis Pharma generates revenue primarily through SKYTROFA, an approved treatment for growth hormone deficiency in children. Beyond its commercial product, the company advances a pipeline of TransCon-based therapies — a prodrug technology designed to release active drug in a controlled, sustained manner. Pipeline programs target adult growth hormone deficiency, hypoparathyroidism, achondroplasia, and oncology applications, positioning the company across multiple rare-disease markets.

Ascendis Pharma was incorporated in 2006 and is headquartered in Hellerup, Denmark.

  • SKYTROFA — approved weekly therapy for pediatric growth hormone deficiency
  • TransCon PTH — investigational treatment for adult hypoparathyroidism
  • TransCon CNP — pipeline candidate for pediatric achondroplasia
  • TransCon hGH — growth hormone therapy in development for adults and Japan
  • Oncology pipeline — TransCon TLR 7/8 and TransCon IL-2 programs

Is ASND a Good Stock to Buy?

UQS Score rates ASND as Good overall, reflecting a company in active commercial and pipeline expansion.

The Growth pillar stands out as the clearest strength, consistent with a company transitioning from early commercialization toward broader market penetration. The Risk pillar also rates favorably, suggesting the company's financial structure and operational profile carry manageable downside relative to peers at a similar stage.

The Quality pillar is currently rated Weak, which is common for biopharmaceuticals still scaling revenue and investing heavily in R&D. Investors should weigh this against the longer-term pipeline opportunity.

See the exact pillar breakdown and full financial metrics by signing up for a UQS Pro account. Sign up free →

Past performance does not guarantee future results. UQS Score is based on fundamental data and is not a buy/sell recommendation.

Does ASND pay dividends?

No — Ascendis Pharma A/S does not currently pay a dividend.

Ascendis Pharma does not currently pay a dividend. For a clinical-stage and early-commercial biopharmaceutical company, this is typical — available capital is directed toward R&D, pipeline advancement, and commercial infrastructure rather than shareholder distributions. Income-focused investors should factor this into their assessment.

When does ASND report earnings?

Ascendis Pharma reports earnings on a quarterly cadence, consistent with US-listed equities.

Quarterly results have reflected the company's ongoing commercial ramp of SKYTROFA alongside continued pipeline investment. Revenue trajectory and operating expense trends are key focal points for investors monitoring the path toward profitability.

For the most recent quarter's results and guidance, visit Ascendis Pharma's investor relations page directly.

ASND Price History

+78.8% over 5Y

Monthly close, adjusted for stock splits and dividend reinvestment.

Return Calculator

What if I invested in Ascendis Pharma A/S?

$
Today it would be worth
$19,219
That's a +92.2% total return, or +14.0% annualized.

Based on Ascendis Pharma A/S's historical closing prices, adjusted for stock splits and dividend reinvestment. Past performance does not guarantee future results. This is for informational purposes only and is not financial advice.

ASND Long-term Outlook

The Strong Growth pillar signals that Ascendis Pharma's fundamental trajectory is among the more compelling in the [healthcare](/sector/healthcare) sector. Commercial expansion of SKYTROFA and potential pipeline approvals represent the primary drivers of that outlook. The Good Risk rating suggests the company is navigating its growth phase with reasonable financial discipline, though the path to sustained profitability remains a key variable to watch.

Growth drivers

  • Continued SKYTROFA commercial uptake in pediatric growth hormone deficiency
  • Pipeline readouts and potential approvals for TransCon PTH and TransCon CNP
  • Geographic expansion of TransCon hGH, including the Japanese market

Key risks

  • Sustained R&D spend weighing on near-term profitability — reflected in the Weak Quality pillar
  • Clinical and regulatory execution risk across multiple pipeline programs
  • Competitive dynamics in rare endocrine and orphan disease markets

ASND vs Peers

Ascendis Pharma operates in a competitive rare-disease and specialty biopharmaceutical landscape alongside several focused peers.

BBIOSimilar UQS
BridgeBio Pharma, Inc.

BridgeBio focuses on genetic diseases with a broad pipeline, but lacks Ascendis's proprietary prodrug delivery platform.

GMABASND scores lower
Genmab A/S

Genmab is a Danish antibody specialist with a more established commercial portfolio, competing in a different therapeutic modality.

JAZZASND scores higher
Jazz Pharmaceuticals plc

Jazz operates as a more diversified specialty pharma company with neuroscience and oncology focus, offering a contrasting risk-revenue profile.

Frequently Asked Questions

What does Ascendis Pharma do?

Ascendis Pharma is a biopharmaceutical company that develops therapies for rare and underserved conditions using its proprietary TransCon prodrug platform. Its lead commercial product, SKYTROFA, treats growth hormone deficiency in children. The pipeline extends into adult endocrine disorders, skeletal dysplasia, and oncology.

Does ASND pay dividends?

No, Ascendis Pharma does not currently pay a dividend. As a company still scaling its commercial operations and investing heavily in pipeline development, available capital is reinvested into the business rather than returned to shareholders through distributions.

When does ASND report earnings?

Ascendis Pharma reports on a quarterly cadence, as is standard for US-listed companies. For specific upcoming reporting dates and the latest financial results, check the investor relations section of the Ascendis Pharma website.

Is ASND a good stock to buy?

UQS Score rates ASND as Good overall. The Growth pillar is a standout strength, while the Quality pillar is currently Weak — reflecting the investment-heavy phase typical of commercial-stage biopharma. Whether it suits your portfolio depends on your risk tolerance and time horizon. View the full pillar breakdown on UQS Pro.

Is ASND overvalued?

The UQS Valuation pillar for ASND is rated Neutral, suggesting the market is pricing the stock in line with its fundamental profile rather than at a clear premium or discount. For the detailed valuation metrics behind this rating, a UQS Pro account provides the complete view.

How does ASND compare to its competitors?

Compared to peers like BridgeBio Pharma, Genmab, and Jazz Pharmaceuticals, Ascendis stands out through its TransCon platform — a differentiated drug-delivery technology applied across multiple rare-disease programs. Each competitor operates with a distinct therapeutic focus and commercial maturity, making direct comparisons nuanced.

What is ASND's market cap bracket?

Ascendis Pharma is classified as a large-cap company. This places it among the more established players in the specialty biopharmaceutical space, despite still being in an active commercial and pipeline growth phase.

Who founded Ascendis Pharma?

Ascendis Pharma was founded by John Fowler and Klaus Klausen, among others, and was incorporated in 2006. The company is headquartered in Hellerup, Denmark. Full founding history is publicly available through the company's official disclosures.

Is ASND a long-term quality investment?

From a long-term quality perspective, ASND's Strong Growth pillar and Good Risk rating are encouraging indicators. However, the Weak Quality pillar reflects the current profitability profile. Long-term quality potential depends on successful pipeline execution and the company's ability to scale revenue relative to its cost base.

What is the main competitive advantage of Ascendis Pharma?

Ascendis Pharma's primary competitive advantage is its TransCon platform — a proprietary prodrug technology that enables controlled, sustained release of active therapeutics. This platform is applied across multiple disease areas, creating a pipeline engine that differentiates Ascendis from companies relying on single-asset strategies.

What sector does ASND belong to?

Ascendis Pharma belongs to the [Healthcare sector](/sector/healthcare), specifically within biopharmaceuticals. The company focuses on rare and specialty diseases, a segment characterized by high unmet need, orphan drug designations, and significant R&D investment requirements.

Is ASND a growth stock or value stock?

Based on UQS pillar labels, ASND leans toward the growth category — the Growth pillar is rated Strong while the Valuation pillar is Neutral. This profile is consistent with a company where investors are pricing in future pipeline and commercial expansion rather than current earnings power.

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Pro Analysis

ASND — Score History

4550556065Apr 2Apr 12Apr 22May 2May 12May 22May 24v5
Score changes· 28 most recent
DateUQSQualityMoatGrowthRiskValueChange
May 23, 202653.435.046.0100.042.245.70.0
May 22, 202653.435.046.0100.042.245.6-0.1
May 21, 202653.535.046.0100.042.245.80.0
May 20, 202653.535.046.0100.042.246.00.0
May 19, 202653.535.046.0100.042.246.10.0
May 17, 202653.535.046.0100.042.245.90.0
May 16, 202653.535.046.0100.042.246.0+0.1
May 15, 202653.435.046.0100.042.245.7-0.1
May 14, 202653.535.046.0100.042.246.1-0.1
May 13, 202653.635.046.0100.042.246.4+0.1

ASND — Pillar Breakdown

Quality

35.0/100 (25%)

Ascendis Pharma A/S has average quality metrics, with room for improvement in margins or capital efficiency.

Capital Efficiency (ROIC)Weak

How effectively capital is deployed to generate returns.

Return on EquityWeak

Profitability relative to shareholders' equity.

Operating ProfitabilityWeak

Ability to convert revenue into operating profit.

Net ProfitabilityStrong

Bottom-line profit as a share of revenue.

Gross Profit / AssetsStrong

Asset productivity — how much gross profit each dollar of assets generates.

Cash GenerationWeak

Free cash flow relative to market value.

Growth

100.0/100 (20%)

Ascendis Pharma A/S is growing rapidly with strong revenue and earnings expansion.

Recent Revenue TrendStrong

Revenue trajectory over the last twelve months.

3Y Revenue CAGRStrong

Compound annual revenue growth rate over 3 years.

EPS GrowthStrong

Year-over-year earnings per share growth.

Forward Revenue OutlookStrong

Analyst consensus for future revenue growth.

Forward EPS GrowthStrong

Analyst consensus for future earnings growth.

Risk

42.2/100 (15%)

Ascendis Pharma A/S has some risk factors including moderate leverage or solvency concerns.

Financial LeverageStrong

Debt levels relative to earnings capacity.

Debt/EquityWeak

Total debt relative to shareholder equity.

Current RatioWeak

Short-term liquidity — ability to pay near-term obligations.

Interest CoverageWeak

Earnings capacity relative to interest payments.

Valuation

45.7/100 (15%)

Ascendis Pharma A/S has a mixed valuation — some metrics suggest fair value while others appear stretched.

Earnings YieldWeak

Inverse of forward P/E — higher yield means cheaper stock.

Price to Free Cash FlowWeak

How many years of FCF the market cap represents.

PEG RatioStrong

P/E relative to earnings growth — lower is more attractive.

Moat

46/100 (25%)

Ascendis Pharma A/S possesses some competitive advantages but faces meaningful competition. The Moat pillar evaluates competitive advantages across five dimensions: Switching Costs, Network Effects, Cost Advantage, Intangible Assets, and Scale & Ecosystem. Sign in to customize moat ratings for ASND.

Score Composition

Quality
35.0×25%8.8
Growth
100.0×20%20.0
Risk
42.2×15%6.3
Valuation
45.7×15%6.9
Moat
46.0×25%11.5
Total
53.4Good

Financial Data

More Stock Analysis

How is the ASND UQS Score Calculated?

The UQS (Unified Quality Score) for Ascendis Pharma A/S is calculated using a proprietary 6-pillar framework with 29 financial metrics. Each pillar evaluates a different dimension on a 0–100 scale, then combines into a single weighted score. Scoring thresholds are calibrated per sector. Momentum is an optional Pro toggle — without it, you get the 5-pillar / 25-metric core shown below.

Quality (25%) measures profitability and capital efficiency — ROIC, ROE, margins, GP/Assets, and FCF Yield.

Moat (25%) assesses Ascendis Pharma A/S's competitive advantages across switching costs, network effects, cost advantages, intangible assets, and ecosystem scale.

Growth (20%) tracks revenue trajectory and earnings momentum, combining historical results with analyst forward estimates.

Risk (15%) is inversely scored — lower leverage and strong balance sheet health result in higher scores.

Valuation (15%) measures whether Ascendis Pharma A/S is fairly priced using earnings yield, price-to-FCF, PEG ratio, and EV/EBITDA relative to sector peers.

Six investor-inspired presets are available, each with different pillar weights: Balanced, Buffett, Munger, Lynch, Cathie Wood, and Graham. The public score shown here uses the Balanced preset. Learn more in our FAQ.