ARVN
HealthcareArvinas, Inc. · Biotechnology · $590M
What is Arvinas, Inc.?
Arvinas, Inc. is a clinical-stage biopharmaceutical company pioneering a novel class of therapies designed to eliminate disease-causing proteins from the body. Founded in 2013 and headquartered in New Haven, Connecticut, Arvinas is built around its proprietary PROTAC protein degrader platform.
Arvinas develops PROTAC (proteolysis targeting chimera) protein degraders — molecules engineered to direct the body's own cellular machinery to destroy proteins that drive disease. Unlike traditional drugs that merely block a protein, PROTACs aim to remove it entirely. The company's pipeline targets cancers driven by the androgen receptor and estrogen receptor. Arvinas funds its research partly through collaborations with major pharmaceutical partners including Pfizer, Genentech, Roche, and Bayer.
Arvinas was founded in 2013 and operates out of New Haven, Connecticut.
- Bavdegalutamide — PROTAC targeting androgen receptor in prostate cancer
- ARV-471 — PROTAC targeting estrogen receptor in breast cancer
- ARV-766 — oral PROTAC investigational therapy for prostate cancer
- PROTAC protein degrader discovery platform
- Pharma collaborations with Pfizer, Genentech, Roche, and Bayer
Is ARVN a Good Stock to Buy?
UQS Score rates ARVN as Poor overall, reflecting the early-stage nature of its business and the significant uncertainties that come with clinical-stage drug development.
Among the five pillars, Risk stands out as the relative bright spot — suggesting the company carries a manageable near-term financial risk profile compared to many peers at a similar stage. This is partly attributable to its pharma partnership structure, which provides non-dilutive funding.
Quality, Moat, and Growth all register as Weak, which is typical for pre-revenue biotechs without approved products. Valuation is rated Elevated, meaning the current market price already embeds significant optimism about pipeline success.
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Past performance does not guarantee future results. UQS Score is based on fundamental data and is not a buy/sell recommendation.
Does ARVN pay dividends?
No — Arvinas, Inc. does not currently pay a dividend.
Arvinas does not pay a dividend, which is standard for clinical-stage biotechs. All available capital is directed toward research, clinical trials, and pipeline advancement. Investors in ARVN are positioned for potential long-term capital appreciation tied to drug development outcomes rather than income generation.
When does ARVN report earnings?
Arvinas reports financial results on a quarterly cadence, consistent with US-listed public companies.
As a pre-revenue clinical-stage company, Arvinas's quarterly results center on cash runway, operating expenses, and collaboration revenue rather than product sales. Progress in clinical trials and partnership milestones tend to be the most market-moving disclosures.
For the most recent quarter's results and pipeline updates, visit Arvinas's investor relations page directly.
ARVN Price History
-85.4% over 5Y
Monthly close, adjusted for stock splits and dividend reinvestment.
What if I invested in Arvinas, Inc.?
Based on Arvinas, Inc.'s historical closing prices, adjusted for stock splits and dividend reinvestment. Past performance does not guarantee future results. This is for informational purposes only and is not financial advice.
ARVN Long-term Outlook
Arvinas's fundamental outlook is shaped by binary clinical risk — pipeline readouts for its lead PROTAC candidates will be the primary value drivers. The Growth pillar rating of Weak reflects the absence of commercial revenue today, though successful trial outcomes could shift that trajectory materially. The Elevated Valuation pillar signals that the market has already priced in a degree of pipeline optimism, leaving limited margin for setbacks.
Growth drivers
- Potential clinical advancement of ARV-471 in ER-positive breast cancer
- Expanding PROTAC platform with multiple oncology indications
- Milestone and royalty payments from Pfizer, Roche, and Bayer collaborations
Key risks
- Clinical trial failure or delays across lead pipeline candidates
- Elevated valuation leaves little room for disappointing data
- Ongoing cash burn typical of pre-revenue biotech operations
ARVN vs Peers
Arvinas operates in a competitive landscape of clinical-stage and early-commercial biotechs pursuing novel therapeutic modalities.
Alpha Tau focuses on alpha radiation therapy for solid tumors, a distinct physical oncology approach compared to Arvinas's protein degradation biology.
Bright Minds targets neurological and psychiatric disorders through serotonin receptor modulation, operating in a different therapeutic area than Arvinas's oncology focus.
Prime Medicine pursues gene editing via its Prime Editing platform, representing a different biological intervention strategy from Arvinas's targeted protein degradation approach.
Frequently Asked Questions
What does Arvinas do?
Arvinas is a clinical-stage biopharmaceutical company developing PROTAC protein degraders — a novel class of molecules that direct the body's own cellular machinery to destroy disease-causing proteins. Its pipeline focuses primarily on cancers driven by the androgen receptor and estrogen receptor, with collaborations supporting its research.
Does ARVN pay dividends?
No, Arvinas does not pay a dividend. As a clinical-stage company with no approved products, it reinvests all capital into research and clinical development. Investors in ARVN are seeking potential capital appreciation from pipeline progress rather than income.
When does ARVN report earnings?
Arvinas reports on a quarterly cadence, standard for US-listed public companies. Because it is pre-revenue, the most watched disclosures are clinical trial updates and collaboration milestones. Check Arvinas's investor relations page for the current reporting schedule.
Is ARVN a good stock to buy?
UQS Score rates ARVN as Poor overall, driven by Weak ratings across Quality, Moat, and Growth pillars and an Elevated Valuation. That profile reflects the high uncertainty inherent in clinical-stage biotech investing. The full pillar breakdown is available to UQS Pro members.
Is ARVN overvalued?
The UQS Valuation pillar for ARVN is rated Elevated, indicating the current market price embeds meaningful optimism about future pipeline success. For a pre-revenue biotech, valuation is largely driven by probability-weighted clinical outcomes rather than current financials.
How does ARVN compare to its competitors?
Arvinas competes in the broader clinical-stage biotech space. Compared to peers like Alpha Tau Medical, Bright Minds Biosciences, and Prime Medicine, Arvinas is differentiated by its PROTAC platform and its high-profile pharma collaborations with Pfizer and Roche. Each company pursues distinct therapeutic modalities.
What is ARVN's market cap bracket?
Arvinas is classified as a small-cap stock. This reflects its pre-commercial stage — the company has not yet generated product revenue, and its market value is driven by pipeline potential and partnership agreements rather than earnings.
Who founded Arvinas?
Arvinas was founded in 2013. The company's founding is rooted in academic research on targeted protein degradation. Detailed founding history, including key individuals involved, is widely available through Arvinas's public disclosures and investor relations materials.
Is ARVN a long-term quality investment?
From a long-term quality perspective, ARVN's UQS profile currently rates as Poor, with Weak scores across Quality, Moat, and Growth. Long-term quality indicators would need to improve — particularly through clinical success and eventual commercialization — before the profile strengthens materially.
What is the main competitive advantage of Arvinas?
Arvinas's primary differentiator is its proprietary PROTAC protein degrader platform, which targets disease-causing proteins for elimination rather than mere inhibition. This approach has attracted partnerships with major pharmaceutical companies, providing both validation and non-dilutive funding to support its pipeline.
What sector does ARVN belong to?
Arvinas operates in the Healthcare sector, specifically within clinical-stage biopharmaceuticals. Its focus on oncology and novel protein degradation biology places it in one of the more research-intensive and risk-bearing segments of the healthcare industry.
Is ARVN a growth stock or value stock?
Based on UQS pillar labels, ARVN carries a Weak Growth rating and an Elevated Valuation rating — a combination that does not fit neatly into either category. It is best understood as a speculative clinical-stage biotech where value depends almost entirely on pipeline outcomes.
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Pro Analysis
ARVN — Score History
| Date | UQS | Quality | Moat | Growth | Risk | Value | Change |
|---|---|---|---|---|---|---|---|
| May 14, 2026 | 27.6 | 15.0 | 22.0 | 37.7 | 72.1 | 0.0 | +1.5 |
| May 11, 2026 | 26.1 | 15.0 | 22.0 | 37.7 | 62.3 | 0.0 | +3.7 |
| May 10, 2026 | 22.4 | 0.0 | 22.0 | 37.7 | 62.3 | 0.0 | -3.7 |
| Apr 2, 2026 | 26.1 | 15.0 | 22.0 | 37.7 | 62.3 | 0.0 | — |
ARVN — Pillar Breakdown
Quality
— 15.0/100 (25%)Arvinas, Inc. currently shows below-average quality metrics, suggesting challenges with profitability.
How effectively capital is deployed to generate returns.
Profitability relative to shareholders' equity.
Ability to convert revenue into operating profit.
Bottom-line profit as a share of revenue.
Asset productivity — how much gross profit each dollar of assets generates.
Free cash flow relative to market value.
Growth
— 37.7/100 (20%)Arvinas, Inc. shows steady but unspectacular growth, typical for mature companies.
Revenue trajectory over the last twelve months.
Compound annual revenue growth rate over 3 years.
Year-over-year earnings per share growth.
Analyst consensus for future revenue growth.
Risk
— 72.1/100 (15%)Arvinas, Inc. maintains a reasonable risk profile with manageable debt levels.
Debt levels relative to earnings capacity.
Total debt relative to shareholder equity.
Short-term liquidity — ability to pay near-term obligations.
Earnings capacity relative to interest payments.
Valuation
— 0.0/100 (15%)Arvinas, Inc. appears expensively valued relative to its fundamentals and growth prospects.
Moat
— 22/100 (25%)Arvinas, Inc. operates in a highly competitive environment with limited sustainable advantages. The Moat pillar evaluates competitive advantages across five dimensions: Switching Costs, Network Effects, Cost Advantage, Intangible Assets, and Scale & Ecosystem. Sign in to customize moat ratings for ARVN.
Score Composition
Financial Data
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How is the ARVN UQS Score Calculated?
The UQS (Unified Quality Score) for Arvinas, Inc. is calculated using a proprietary 6-pillar framework with 29 financial metrics. Each pillar evaluates a different dimension on a 0–100 scale, then combines into a single weighted score. Scoring thresholds are calibrated per sector. Momentum is an optional Pro toggle — without it, you get the 5-pillar / 25-metric core shown below.
Quality (25%) measures profitability and capital efficiency — ROIC, ROE, margins, GP/Assets, and FCF Yield.
Moat (25%) assesses Arvinas, Inc.'s competitive advantages across switching costs, network effects, cost advantages, intangible assets, and ecosystem scale.
Growth (20%) tracks revenue trajectory and earnings momentum, combining historical results with analyst forward estimates.
Risk (15%) is inversely scored — lower leverage and strong balance sheet health result in higher scores.
Valuation (15%) measures whether Arvinas, Inc. is fairly priced using earnings yield, price-to-FCF, PEG ratio, and EV/EBITDA relative to sector peers.
Six investor-inspired presets are available, each with different pillar weights: Balanced, Buffett, Munger, Lynch, Cathie Wood, and Graham. The public score shown here uses the Balanced preset. Learn more in our FAQ.